To better understand the barriers associated with adoption and use of e-prescribing of controlled substances (EPCS), a practice recently established by the U.S. Drug Enforcement Administration (DEA), Cindy Parks Thomas, PhD, a professor at Brandeis University in Waltham, Mass., and colleagues in a Sept. 21 article in the Journal of the American Medical Informatics Association, described their research on e-prescribing of controlled substances.