MICAD adds 25 agents
The Molecular Imaging and Contrast Agent Database (MICAD), which provides free online scientific information regarding in vivo molecular imaging and contrast agents, has added 25 agents to its database.
The new agents are:
PET
1. 4-[18F]F-T140 Target: Chemokine receptor 4 (CXCR4)
2. 68Ga-NOTA-NI Target: Hypoxic tissue
3. 86Y-CHX-A''-DTPA-bevacizumab Target: Vascular endothelial growth factor-A (VEGF-A)
4. [18F]FAC Target: Deoxycytidine kinase (DCK)
5. 2’-[18F]FFA Target: Putative folate receptor
6. [11C]Papaverine Target: Phosphodiesterase type 10A
7. [18F]JNJ41510417 Target: Phosphodiesterase type 10A
8. [18F]-PFH Target: Organic anion transporter 1 (OAT1)
9. [89Zr]-ranibizumab Target: Vascular endothelial growth factor-A (VEGF-A)
10. 68Ga-NOTA-PEG-scVEGF Target: Vascular endothelial growth factor receptor-2 (VEGFR-2)
11. 68Ga-HBED-CC-PEG-scVEGF Target: Vascular endothelial growth factor receptor-2 (VEGFR-2)
Gamma planar imaging and SPECT
12. 99mTc-DTPA-mannosyl-dextran Target: Macrophage mannose receptors (MRCs), mannose binding protein (MBP) or CD206
13. [125I]SGMIB-L8A4 Target: Epidermal growth factor receptor variant III (EGFRvIII)
14. [177Lu]C-DOTA-L8A4 Target: Epidermal growth factor receptor variant III (EGFRvIII)
15. [177Lu]CHX-A?-DTPA-L8A4 Target: Epidermal growth factor receptor variant III (EGFRvIII)
16. [177Lu]1B4M-DTPA-L8A4 Target: Epidermal growth factor receptor variant III (EGFRvIII)
17. [177Lu]MeO-DOTA-L8A4 Target: Epidermal growth factor receptor variant III (EGFRvIII)
Optical Imaging
18. DY-g7-PLGA NPs Target: Opioid receptors
19. QT Target: Epidermal growth factor receptor (EGFR), HER2
20. QD655-PSMA or QD655-J591 Target: Prostate-specific membrane antigen (PSMA), folate hydrolase
Multimodality
21. Lenti-myc-hFTH Target: Cells
22. PTP-CLIO-Cy5.5 Target: Plectin-1
MRI
23. Alkyl-PEI2k/SPIO Target: Cells (mesenchymal stem cell labeling)
X-Ray/CT
24. AuNPs Target: Non-targeted
Ultrasound
25. scVEGF-MBs Target: Vascular endothelial growth factor receptor-2 (VEGFR-2)
The new agents are:
PET
1. 4-[18F]F-T140 Target: Chemokine receptor 4 (CXCR4)
2. 68Ga-NOTA-NI Target: Hypoxic tissue
3. 86Y-CHX-A''-DTPA-bevacizumab Target: Vascular endothelial growth factor-A (VEGF-A)
4. [18F]FAC Target: Deoxycytidine kinase (DCK)
5. 2’-[18F]FFA Target: Putative folate receptor
6. [11C]Papaverine Target: Phosphodiesterase type 10A
7. [18F]JNJ41510417 Target: Phosphodiesterase type 10A
8. [18F]-PFH Target: Organic anion transporter 1 (OAT1)
9. [89Zr]-ranibizumab Target: Vascular endothelial growth factor-A (VEGF-A)
10. 68Ga-NOTA-PEG-scVEGF Target: Vascular endothelial growth factor receptor-2 (VEGFR-2)
11. 68Ga-HBED-CC-PEG-scVEGF Target: Vascular endothelial growth factor receptor-2 (VEGFR-2)
Gamma planar imaging and SPECT
12. 99mTc-DTPA-mannosyl-dextran Target: Macrophage mannose receptors (MRCs), mannose binding protein (MBP) or CD206
13. [125I]SGMIB-L8A4 Target: Epidermal growth factor receptor variant III (EGFRvIII)
14. [177Lu]C-DOTA-L8A4 Target: Epidermal growth factor receptor variant III (EGFRvIII)
15. [177Lu]CHX-A?-DTPA-L8A4 Target: Epidermal growth factor receptor variant III (EGFRvIII)
16. [177Lu]1B4M-DTPA-L8A4 Target: Epidermal growth factor receptor variant III (EGFRvIII)
17. [177Lu]MeO-DOTA-L8A4 Target: Epidermal growth factor receptor variant III (EGFRvIII)
Optical Imaging
18. DY-g7-PLGA NPs Target: Opioid receptors
19. QT Target: Epidermal growth factor receptor (EGFR), HER2
20. QD655-PSMA or QD655-J591 Target: Prostate-specific membrane antigen (PSMA), folate hydrolase
Multimodality
21. Lenti-myc-hFTH Target: Cells
22. PTP-CLIO-Cy5.5 Target: Plectin-1
MRI
23. Alkyl-PEI2k/SPIO Target: Cells (mesenchymal stem cell labeling)
X-Ray/CT
24. AuNPs Target: Non-targeted
Ultrasound
25. scVEGF-MBs Target: Vascular endothelial growth factor receptor-2 (VEGFR-2)