MICAD adds 25 agents

Manjula Puthenedam, PhD, | | Health Exec | EMR/EHR
The Molecular Imaging and Contrast Agent Database (MICAD), which provides free online scientific information regarding in vivo molecular imaging and contrast agents, has added 25 agents to its database.

The new agents are:

PET
1.    4-[18F]F-T140     Target:    Chemokine receptor 4 (CXCR4)
2.    68Ga-NOTA-NI     Target:    Hypoxic tissue
3.    86Y-CHX-A''-DTPA-bevacizumab    Target:   Vascular endothelial growth factor-A (VEGF-A)
4.    [18F]FAC    Target:    Deoxycytidine kinase (DCK)
5.    2’-[18F]FFA     Target:    Putative folate receptor
6.    [11C]Papaverine     Target:    Phosphodiesterase type 10A
7.    [18F]JNJ41510417     Target:    Phosphodiesterase type 10A
8.    [18F]-PFH     Target:    Organic anion transporter 1 (OAT1)
9.    [89Zr]-ranibizumab    Target:    Vascular endothelial growth factor-A (VEGF-A)
10.    68Ga-NOTA-PEG-scVEGF   Target: Vascular endothelial growth factor receptor-2 (VEGFR-2)
11.    68Ga-HBED-CC-PEG-scVEGF  Target:  Vascular endothelial growth factor receptor-2 (VEGFR-2)

Gamma planar imaging and SPECT
12.    99mTc-DTPA-mannosyl-dextran    Target:   Macrophage mannose receptors (MRCs), mannose binding protein (MBP) or CD206
13.    [125I]SGMIB-L8A4   Target:   Epidermal growth factor receptor variant III (EGFRvIII)
14.    [177Lu]C-DOTA-L8A4    Target:   Epidermal growth factor receptor variant III (EGFRvIII)
15.    [177Lu]CHX-A?-DTPA-L8A4  Target: Epidermal growth factor receptor variant III (EGFRvIII)
16.    [177Lu]1B4M-DTPA-L8A4   Target:  Epidermal growth factor receptor variant III (EGFRvIII)
17.    [177Lu]MeO-DOTA-L8A4   Target:  Epidermal growth factor receptor variant III (EGFRvIII)

Optical Imaging
18.    DY-g7-PLGA NPs   Target:  Opioid receptors
19.    QT   Target:   Epidermal growth factor receptor (EGFR), HER2
20.    QD655-PSMA or QD655-J591   Target:   Prostate-specific membrane antigen (PSMA), folate hydrolase

Multimodality
21.    Lenti-myc-hFTH   Target:   Cells
22.    PTP-CLIO-Cy5.5   Target:   Plectin-1

MRI
23.    Alkyl-PEI2k/SPIO   Target: Cells (mesenchymal stem cell labeling)

X-Ray/CT 
24.    AuNPs   Target:   Non-targeted

Ultrasound
25.    scVEGF-MBs   Target:   Vascular endothelial growth factor receptor-2 (VEGFR-2)

Manjula Puthenedam, PhD,

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